Natural therapy against cancerous tumors, according to Jerry McLaughlin from Purdue University in Lafayette, Indiana. See document.
Graviola comes from pulverized Annona muricata leaves, which contain acetogenins that reduce cancerous tumors; they reduce prostate-specific antigens (PSA) considerably, contributing to preventing and reducing soft tumors and metastases. Hence, this is an anti-cancer plant. It has been used by Peruvian indigenous people to treat many diseases: Graviola also has anti-microbial and anti-parasitic properties.
GRAVIOLA (Annona muricata) is the soursop tree, whose leaves contain waxy substances called acetogenins (more than 10 of them) that have the ability to act selectively on cancer cells and destroy them, thus reducing the tumor size without affecting healthy cells.
Acetogenins result from a combination of long-chain fatty acids (C32 or C34) with a 2-propanol unit at carbon 2, forming a terminal lactone (this lactone is at the beginning of the chain). Like other acetogenins, annonacin blocks Complex 1, which is responsible for converting NADH to NAD+ and creates a proton accumulation through the internal mitochondrial membrane. Annonacin deactivates a cell’s ability to generate ATP through an oxidative route, eventually forcing the cell into apoptosis or necrosis (death).
An in-vitro study jointly performed by the Faculty of Pharmacy and Biochemistry of the National University of San Marcos and the Peruvian Cayetano Heredia University has shown that an ethanolic extract from GRAVIOLA leaves has a cytotoxic effect on type C678 and H460 gastric and pulmonary adenocarcinoma cell line cultures.
There are numerous graviola studies, of which we are going to mention only the following: studies performed from 1998 to 2000 by McLaughlin, Chih HW, and Chui HF, where they show that the acetogenins are inhibitors of Complex 1 from the oxidative phosphorylation chain, which is why they block ATP formation and thus the energy needed by the cancer cell to operate the P-glycoprotein-driven pump that enables it to stay active. The acetogenins also inhibit ubiquinone oxidase, an NADH-dependent enzyme that is characteristic of a cancer cell’s plasma membrane. McLaughlin conducted his research with the two acetogenins bullatacin and bullatacinone.
100-capsule bottle (500 mg / 0.018 oz capsules)
Keep container tightly-closed. Store in a fresh and dry place, and keep away from light.
There are no reports of secondary effects, except in some people at very high doses, at which moderate diarrhea may appear. This is why it is recommended to increase the dose only gradually.
When taking the capsules according to the recommended doses and frequencies, no adverse secondary effects can be observed. This indication is no (medical) prescription, so it does not replace an appointment with the doctor. Keep away from children.
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